Fellows' Presentation

Deciphering the Evolution of a Cancer, One Cell at a Time

Photo by Tony RinaldoPhoto by Tony Rinaldo

Part of the 2014–2015 Fellows' Presentation Series

Lecture by Itai Yanai RI '15


During the fellowship year, Itai Yanai is working in Aviv Regev’s laboratory at the Broad Institute of the Massachusetts Institute of Technology and Harvard University on deciphering the evolutionary history of cancerous growths. Yanai is asking whether studying individual cancer cells using approaches from the field of evolutionary developmental biology can reveal the genetic history of particular growths. He seeks to determine, within a given cancer, the order of occurrence of those mutations that defined its evolutionary course, which may be helpful in predicting its trajectory.