Jané Kondev is a theoretical physicist working on problems in biology. He combines mathematical modeling and quantitative experimentation to obtain quantitative models of living matter. Current projects include DNA damage repair in yeast, regulation of transcription in bacteria, assembly of viruses, and chromosome organization in E. coli.
During the fellowship year, Kondev will do research on chromosome organization in bacteria and yeast, in collaboration with experimental labs at Harvard University, the Massachusetts Institute of Technology, and Brandeis University. He will focus on the question of how chromosome territories—regions of the cell to which genes are confined—are established and maintained, and what their role is in the life of a cell. Kondev will also use his time at Radcliffe to complete the book “Physical Biology of the Cell,” whose aim is to develop quantitative intuition about biological macromolecules and cells. The book makes use of simple physical models to provide a mathematical description of life’s processes.
Kondev obtained his PhD in theoretical physics from Cornell University and spent time as a postdoctoral fellow at Brown University and at the Institute for Advanced Study in Princeton, New Jersey. He was the recipient of the CAREER award from the National Science Foundation and was a Cotrell Scholar of the Research Corporation. He is a codirector of the quantitative biology program at Brandeis, funded by the Howard Hughes Medical Institute, which provides cross-disciplinary graduate education for students in the physical and biomedical fields.